John A Chaddock : rechercher sur Z-Library

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Articles (35)
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Engineered Botulinum Neurotoxins as New Therapeutics

Masuyer, Geoffrey, Chaddock, John A., Foster, Keith A., Acharya, K. Ravi

Journal:

Annual Review of Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2014

Major Structural Differences between Pokeweed Antiviral Protein and Ricin A-Chain do not Account for their Differing Ribosome Specificity

John A. Chaddock, Arthur F. Monzingo, Jon D. Robertus, J. Michael Lord, Lynne M. Roberts

Journal:

FEBS Journal

Année:

1996

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1996

Chimeras of anthrax toxin and botulinum neurotoxin as novel analgesic proteins

Yang, Nicole, Liu, Sai Man, Marlin, Sandra, Lewandowska, Agnieszka, Heyang, Michelle, Voisin, Tiphaine, Tripathi, Vineeta, Kalinichev, Mikhail, Chaddock, John, Collier, R John, Foster, Keith, Chiu, Is

Journal:

Toxicon

Année:

2018

Fichier:

PDF, 106 KB

2018

Retargeted clostridial endopeptidases: Inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain

John A. Chaddock, John R. Purkiss, Frances C.G. Alexander, Sarah Doward, Sarah J. Fooks, Lorna M. Friis, Yper H.J. Hall, Elizabeth R. Kirby, Nicola Leeds, Hilary J. Moulsdale, Anthony Dickenson, G. Ma

Journal:

Movement Disorders

Année:

2004

Langue:

english

Fichier:

PDF, 135 KB

english, 2004

Transient natural convection in a rectangular enclosure with one heated side wall

John D. Hall, Adrian Bejan, Jack B. Chaddock

Journal:

International Journal of Heat and Fluid Flow

Année:

1988

Langue:

english

Fichier:

PDF, 707 KB

english, 1988

Engineering toxins for 21st century therapies

John A. Chaddock, K. Ravi Acharya

Journal:

FEBS Journal

Année:

2011

Langue:

english

Fichier:

PDF, 178 KB

english, 2011

Engineering botulinum neurotoxin domains for activation by toxin light chain

Patrick R. Stancombe, Geoffrey Masuyer, Ian Birch-Machin, Matthew Beard, Keith A. Foster, John A. Chaddock, K. Ravi Acharya

Journal:

FEBS Journal

Année:

2012

Langue:

english

Fichier:

PDF, 475 KB

english, 2012

Novel application of an in vitro technique to the detection and quantification of botulinum neurotoxin antibodies

Yper H.J Hall, John A Chaddock, Hilary J Moulsdale, Elizabeth R Kirby, Frances C.G Alexander, James D Marks, Keith A Foster

Journal:

Journal of Immunological Methods

Année:

2004

Langue:

english

Fichier:

PDF, 164 KB

english, 2004

The Michigan equine monitoring system. I. Design, implementation and population estimates

John B. Kaneene, Martin Saffell, Don J. Fedewa, Kenneth Gallagher, H.Michael Chaddock

Journal:

Preventive Veterinary Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 823 KB

english, 1997

Botulinum and tetanus neurotoxins: structure, function and therapeutic utility

Kathryn Turton, John A Chaddock, K.Ravi Acharya

Journal:

Trends in Biochemical Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 563 KB

english, 2002

The structure and function of ribosome-inactivating proteins

Martin R. Hartley, John A. Chaddock, Maureen S. Bonness

Journal:

Trends in Plant Science

Année:

1996

Langue:

english

Fichier:

PDF, 2.02 MB

english, 1996

Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A

Geoffrey Masuyer, Nethaji Thiyagarajan, Peter L. James, Philip M.H. Marks, John A. Chaddock, K. Ravi Acharya

Journal:

Biochemical and Biophysical Research Communications

Année:

2009

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2009

Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B

Geoffrey Masuyer, Matthew Beard, Verity A. Cadd, John A. Chaddock, K. Ravi Acharya

Journal:

Journal of Structural Biology

Année:

2011

Langue:

english

Fichier:

PDF, 583 KB

english, 2011

Preparation of specifically activatable endopeptidase derivatives of Clostridium botulinum toxins type A, B, and C and their applications

J. Mark Sutton, Jonathan Wayne, Anthony Scott-Tucker, Susan M. O’Brien, Philip M.H. Marks, Frances C.G. Alexander, Clifford C. Shone, John A. Chaddock

Journal:

Protein Expression and Purification

Année:

2005

Langue:

english

Fichier:

PDF, 453 KB

english, 2005

Restoration of lectin activity to a non-glycosylated ricin B chain mutant by the introduction of a novel N-glycosylation site

Jinbiao Zhan, Michelle de Sousa, John A. Chaddock, Lynne M. Roberts, J.Michael Lord

Journal:

FEBS Letters

Année:

1997

Langue:

english

Fichier:

PDF, 601 KB

english, 1997

Expression and purification of catalytically active, non-toxic endopeptidase derivatives of Clostridium botulinum toxin type A

John A. Chaddock, Michael H. Herbert, Roger J. Ling, Frances C.G. Alexander, Sarah J. Fooks, Dean F. Revell, Conrad P. Quinn, Clifford C. Shone, Keith A. Foster

Journal:

Protein Expression and Purification

Année:

2002

Langue:

english

Fichier:

PDF, 238 KB

english, 2002

Isolation of the gene and large-scale expression and purification of recombinant Erythrina cristagalli lectin

Patrick R Stancombe, Frances C.G Alexander, Roger Ling, Mary A Matheson, Clifford C Shone, John A Chaddock

Journal:

Protein Expression and Purification

Année:

2003

Langue:

english

Fichier:

PDF, 503 KB

english, 2003

White matter microstructure is associated with cognitive control in children

Chaddock-Heyman, Laura, Erickson, Kirk I., Voss, Michelle W., Powers, John P., Knecht, Anya M., Pontifex, Matthew B., Drollette, Eric S., Moore, R. Davis, Raine, Lauren B., Scudder, Mark R., Hillman,

Journal:

Biological Psychology

Année:

2013

Langue:

english

Fichier:

PDF, 852 KB

english, 2013

A Conjugate Composed of Nerve Growth Factor Coupled to a Non-toxic Derivative of Clostridium botulinum Neurotoxin Type A can Inhibit Neurotransmitter Release in Vitro

Chaddock, John A., Purkiss, John R., Duggan, Michael J., Quinn, Conrad P., Shone, Clifford C., Foster, Keith A.

Journal:

Growth Factors

Année:

2000

Langue:

english

Fichier:

PDF, 807 KB

english, 2000

Mutagenesis and kinetic analysis of the active site Glu177 of ricin A-chain

Chaddock, John A., Roberts, Lynne M.

Journal:

Protein Engineering Design and Selection

Année:

1993

Langue:

english

Fichier:

PDF, 3.97 MB

english, 1993

Pokeweed antiviral protein (PAP) mutations which permit E.coli growth do not eliminate catalytic activity towards prokaryotic ribosomes

Chaddock, John A., Lord, J.Michael, Hartley, Martin R., Roberts, Lynne M.

Journal:

Nucleic Acids Research

Année:

1994

Langue:

english

Fichier:

PDF, 4.10 MB

english, 1994

Targeted Secretion Inhibitors—Innovative Protein Therapeutics

Keith, Foster, John, Chaddock

Journal:

Toxins

Année:

2010

Langue:

english

Fichier:

PDF, 129 KB

english, 2010

Do Athletes Excel At Everyday Tasks?

Chaddock, Laura, Neider, Mark B., Voss, Michelle W., Gaspar, John G., Kramer, Arthur F.

Journal:

Medicine & Science in Sports & Exercise

Année:

2011

Langue:

english

Fichier:

PDF, 5.93 MB

english, 2011

Enhancing nontechnical skills, knowledge, aptitudes, and attitudes through veterinary leadership development programs

Lloyd, James W., Chaddock, H. Michael, Hoblet, Kent H., Bayly, Warwick M., Albers, John W., Burge, Gary D.

Journal:

Journal of the American Veterinary Medical Association

Année:

2007

Langue:

english

Fichier:

PDF, 322 KB

english, 2007

Manipulation of Signal Transduction by Botulinum Neurotoxins and their Derivatives

Chaddock, John, Foster, Keith

Journal:

Current Signal Transduction Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 118 KB

english, 2007

Re-engineering the target specificity of clostridial neurotoxins - a route to novel therapeutics

Foster, Keith A., Adams, Emily J., Durose, Lyndsey, Cruttwell, Caroline J., Marks, Elizabeth, Shone, Clifford C., Chaddock, John A., Cox, Clare L., Heaton, Charlotte, Sutton, J. Mark, Wayne, Jonathan,

Journal:

Neurotoxicity Research

Année:

2006

Langue:

english

Fichier:

PDF, 330 KB

english, 2006

Botulinum Neurotoxin A and Neurotoxin E Cleavage Products of Synaptosome-Associated Protein of 25 kd Exhibit Distinct Actions on Pancreatic Islet β-Cell Kv2.1 Channel Gating

He, Yan, Elias, Chadwick L., Huang, Ya-Chi, Gao, Xiaodong, Leung, Yuk-Man, Kang, Youhou, Xie, Huanli, Chaddock, John A., Tsushima, Robert G., Gaisano, Herbert Y.

Journal:

Pancreas

Année:

2008

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2008

Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors

Masuyer, Geoffrey, Davies, Jonathan R., Moore, Kevin, Chaddock, John A., Ravi Acharya, K.

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2015

Engineering destruction sites into botulinum neurotoxins

Lovelock, Laura, Stancombe, Patrick, Laurendon, Amelie, Cadd, Verity, Hackett, Gavin, Foster, Keith, Chaddock, John, Anderson, Dina

Journal:

Toxicon

Année:

2016

Langue:

english

Fichier:

PDF, 47 KB

english, 2016

10.1071/MU02053

Martin, Warren K., Eyears-Chaddock, Melissa, Wilson, Brian R., Lemon, John

Journal:

EMU

Année:

2004

Langue:

english

Fichier:

PDF, 295 KB

english, 2004

TUGS---a tool for teaching computer graphics

Clevenger, John, Chaddock, Rick, Bendig, Roger

Journal:

ACM SIGGRAPH Computer Graphics

Année:

1991

Langue:

english

Fichier:

PDF, 621 KB

english, 1991

Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity

Fonfria, Elena, Elliott, Mark, Beard, Matthew, Chaddock, John, Krupp, Johannes

Journal:

Toxins

Année:

2018

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2018

Numerical modelling of mechanical stresses in bulk superconductor magnets with and without mechanical reinforcement

Ainslie, Mark D, Huang, Kaiyuan, Fujishiro, Hiroyuki, Chaddock, John, Takahashi, Keita, Namba, Sora, Cardwell, David A, Durrell, John Hay

Journal:

Superconductor Science and Technology

Année:

2018

Langue:

english

Fichier:

PDF, 3.94 MB

english, 2018

Phage-assisted continuous evolution of botulinum neurotoxin light chains generates novel light chains with modified snare cleavage specificity

Foster, Keith, Blum, Travis, Beard, Matthew, Chaddock, John, Kupinski, Adam, Harding, Adam, Packer, Michael, Liu, David

Journal:

Toxicon

Année:

2018

Langue:

english

Fichier:

PDF, 186 KB

english, 2018

Genome-wide siRNA screen identification of genes in regulation of BoNT/A trafficking in a sensitized human neuronal stem cell line

Yeo, Jeremy, Beard, Matthew, Chaumet, Alexandre, Krupp, Johannes, Tay, Felicia, Chaddock, John, Foster, Keith, Bard, Frederic

Journal:

Toxicon

Année:

2018

Langue:

english

Fichier:

PDF, 490 KB

english, 2018